Recent Publications

PNAS

Title:

Contractile pericytes determine the direction of blood flow at capillary junctions

Authors:

Albert L. Gonzales, Nicholas R. Klug, Arash Moshkforoush, Jane C. Lee, Frank K. Lee, Bo Shui, Nikolaos M. Tsoukias, Michael I. Kotlikoff, David Hill-Eubanks, and Mark T. Nelson

OCtober 27, 2020

October 13, 2020

JCBFM

Authors:

Amreen Mughal, Adrian M. Sackheim, Maria Sancho-Gonzalez, Thomas A. Longden, Sheila Russell, Warren Lockette, Mark T. Nelson, Kalev Freeman

Title:

Impaired capillary-to-arteriolar electrical signaling after traumatic brain injury 

PNAS

Authors:

Osama F. Harraz, David Hill-Eubanks, Mark T. Nelson

Inaugural PNAS article with QnA with Dr. Nelson

August 25, 2020

Title:

PIP2: A critical regulator of vascular ion channels hiding in plain sight

Authors:

Arash Moshkforoush, Baarbod Ashenagar, Osama F. Harraz, Fabrice Dabertrand, Thomas A. Longden, Mark T. Nelson, Nikolaos M. Tsoukias

july 14, 2020

PNAS

Title:

The capillary Kir channel as sensor and amplifier of neuronal signals: Modeling insights on K+-mediated neurovascular communication

Title:

Reducing Hypermuscularization of the Transitional Segment between Arterioles and Capillaries Protects Against Spontaneous Intracerebral Hemorrhage

Authors:

Julien Ratelade, Nicholas R. Klug, Damiano Lombardi, Monara Kaelle Servulo Cruz Angelim, Fabrice Dabertrand, Valérie Domenga-Denier, Rustam Al-Shahi Salman, Colin Smith, Jean-Frédéric Gerbeau, Mark T. Nelson, Anne Joutel

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MARCH 18, 2020

Circulation

Title:

ATP- and voltage-dependent electro-metabolic signaling regulates blood flow in heart

Authors:

Guiling Zhao, Humberto C. Joca, Mark T. Nelson, and W. Jonathan Lederer

​​

MARCH 13, 2020

PNAS

Title:

Disruption of Pressure-Induced Ca2+ Spark Vasoregulation of Resistance Arteries, Rather Than Endothelial Dysfunction, Underlies Obesity-Related Hypertension

Authors:

Adam S. Greenstein, Sharifah Zamiah Abdul Syed Kadir, Viktoria Csato, Sarah A. Sugden, Rachael A. Baylie, David A. Eisner, Mark T. Nelson

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DEC 23, 2019

Hypertension Editor-in-Chief High Impact selection

Link to paper

Hypertension

May 15, 2019

Authors:

Daniel M. Collier, Nuria Villalba, Adrian Sackheim, Adrian D. Bonev, Zachary D. Miller, Jesse S. Moore, Bo Shui, Jane C. Lee, Frank K. Lee, Shaun Reining, Michael I. Kotlikoff, Mark T. Nelson, and Kalev Freeman

Title:

Extracellular histones induce calcium signals in the endothelium of resistance-sized mesenteric arteries and cause loss of endothelium-dependent dilation

AJP: Heart and Circulatory Physiology

Aug 7, 2018

Title:

PIP2 depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells

Authors:

Osama F. Harraz, Thomas A. Longden, David Hill-Eubanks, Mark T. Nelson

eLife

Authors:

Osama F. Harraz, Thomas A. Longden, Fabrice Dabertrand, David Hill-Eubanks, and Mark T. Nelson

Title:

Endothelial GqPCR activity controls capillary electrical signaling and brain blood flow through PIP2 depletion

March 26, 2018

PNAS

Authors:

Osama F. Harraz, Thomas A. Longden, Fabrice Dabertrand, David Hill-Eubanks, and Mark T. Nelson

Authors:

Thomas A. Longden, Fabrice Dabertrand, Masayo Koide, Albert L. Gonzales, Nathan R. Tykocki, Joseph E. Brayden, David Hill-Eubanks, and Mark T. Nelson

Title:

Capillary K -sensing initiates retrograde hyperpolarization to increase local cerebral blood flow

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Nature Neuroscience News & Views:

"Upstream current for a downstream flow"

Author: Jessica Filosa

March 20, 2017

Nature Neuroscience Cover