Recent Publications

august 5, 2021

Authors:

Masayo Koide, Osama F. Harraz, Fabrice Dabertrand, Thomas A. Longden, Hannah R. Ferris, George C. Wellman, David C. Hill-Eubanks, Adam S. Greenstein, Mark T. Nelson

Title:

Differential restoration of functional hyperemia by antihypertensive drug classes in hypertension-related cerebral small vessel diseases

The Journal of Clinical Investigation

july 21, 2021

Authors:

Thomas A. Longden, Amreen Mughal, Grant W. Hennig, Osama F. Harraz, Bo Shui, Frank K. Lee, Jane C. Lee, Shaun Reining, Michael I. Kotlikoff, Gabriele M. König, Evi Kostenis, David Hill-Eubanks, Mark T. Nelson

Title:

Local IP3 receptor–mediated Ca2+ signals compound to direct blood flow in brain capillaries

Science Advances

JUNE 6, 2021

Authors:

Ashenafi H Betrie, James A Brock, Osama F Harraz, Ashley I Bush, Guo-Wei He, Mark T Nelson, James A Angus, Christine E Wright, Scott Ayton

Title:

Zinc drives vasorelaxation by acting in sensory nerves, endothelium and smooth muscle

Nature Communications

June 8, 2021

Frontiers in Physiology

Authors:

Masayo Koide, Hannah R. Ferris, Mark T. Nelson, and George C. Wellman

Title:

Impaired cerebral autoregulation after subarachnoid hemorrhage: a quantitative assessment using a mouse model

APRIL 27, 2021

PNAS

Authors:

Fabrice Dabertrand, Osama F. Harraz, Masayo Koide, Thomas A. Longden, Amanda C. Rosehart, David C. Hill-Eubanks, Anne Joutel, and Mark T. Nelson

Title:

PIP2 corrects cerebral blood flow deficits in small vessel disease by rescuing capillary Kir2.1 activity

FEBRUARY 22, 2021

Function

COVER ARTICLE 

Authors:

Amreen Mughal, Osama F Harraz, Albert L Gonzales, David Hill-Eubanks, Mark T Nelson

Title:

PIP2 Improves Cerebral Blood Flow in a Mouse Model of Alzheimer's Disease

PNAS

Title:

Contractile pericytes determine the direction of blood flow at capillary junctions

Authors:

Albert L. Gonzales, Nicholas R. Klug, Arash Moshkforoush, Jane C. Lee, Frank K. Lee, Bo Shui, Nikolaos M. Tsoukias, Michael I. Kotlikoff, David Hill-Eubanks, and Mark T. Nelson

OCtober 27, 2020

October 13, 2020

JCBFM

Authors:

Amreen Mughal, Adrian M. Sackheim, Maria Sancho-Gonzalez, Thomas A. Longden, Sheila Russell, Warren Lockette, Mark T. Nelson, Kalev Freeman

Title:

Impaired capillary-to-arteriolar electrical signaling after traumatic brain injury 

PNAS

Authors:

Osama F. Harraz, David Hill-Eubanks, Mark T. Nelson

Inaugural PNAS article with QnA with Dr. Nelson

August 25, 2020

Title:

PIP2: A critical regulator of vascular ion channels hiding in plain sight

Authors:

Arash Moshkforoush, Baarbod Ashenagar, Osama F. Harraz, Fabrice Dabertrand, Thomas A. Longden, Mark T. Nelson, Nikolaos M. Tsoukias

july 14, 2020

PNAS

Title:

The capillary Kir channel as sensor and amplifier of neuronal signals: Modeling insights on K+-mediated neurovascular communication

Title:

Reducing Hypermuscularization of the Transitional Segment between Arterioles and Capillaries Protects Against Spontaneous Intracerebral Hemorrhage

Authors:

Julien Ratelade, Nicholas R. Klug, Damiano Lombardi, Monara Kaelle Servulo Cruz Angelim, Fabrice Dabertrand, Valérie Domenga-Denier, Rustam Al-Shahi Salman, Colin Smith, Jean-Frédéric Gerbeau, Mark T. Nelson, Anne Joutel

​​

MARCH 18, 2020

Circulation

Title:

ATP- and voltage-dependent electro-metabolic signaling regulates blood flow in heart

Authors:

Guiling Zhao, Humberto C. Joca, Mark T. Nelson, and W. Jonathan Lederer

​​

MARCH 13, 2020

PNAS